Usage of "mdr" | TermGallery

Russian

mitteldeutscher rundfunk

Portuguese

mitteldeutscher rundfunk

Spanish

mitteldeutscher rundfunk

Catalan

mitteldeutscher rundfunk

Public broadcaster for the federal states of Thuringia, Saxony and Saxony-Anhalt.

Related terms

german public state broadcaster

mitteldeutscher rundfunk

Portuguese

mdr fernsehen

Spanish

mdr fernsehen

German television station.

mdr fernsehen

Related terms

mdr fernsehen

Spanish

registro de datos de memoria

Register in a computer's processor, or central processing unit, CPU, that stores the data being transferred to and from the immediate access storage.

registro de datos de memoria

Catalan

multiresistència

A microbial organism's resistance to multiple antimicrobial drugs or a cancer cell's resistance to multiple cytostatics.

multiresistència

Synonyms

Examples for "multiple drug resistance"

The xenograft leukemia model with stable multiple drug resistance in nude mice was established. 
 Pubmed 

These results suggest that doxorubicin resistance is multifactorial and alternative mechanisms of multiple drug resistance remain to be determined. 
 Pubmed 

These data cumulatively suggest that the taccalonolides have advantages over the taxanes in their ability to circumvent multiple drug resistance mechanisms. 
 Pubmed 

The multiple drug resistance protein 1 (MRP1 or ABCC1) transports anticancer drugs and normal cell metabolites. 
 Pubmed 

Chemotherapy and targeted therapy can significantly improve survival rates in cancer, but multiple drug resistance (MDR) limits the efficacy of these approaches. 
 Pubmed 

Possible contributors include multidrug resistance, extensive virulence gene content, and ongoing transmission. 
 Pubmed 

The study showed that elevated hsps were not associated with multidrug resistance. 
 Pubmed 

These results hold significant implications for the study of multidrug resistance in vivo. 
 Pubmed 

Silymarin complex was previously described as an antioxidant with multidrug resistance modulation activity. 
 Pubmed 

We are concerned about the multidrug resistance of A. baumannii in this study. 
 Pubmed 

Although more subjective, there is also no consensus regarding the definition of multiresistance. 
 Pubmed 

Cases of multi-drug resistance were recorded in the present study and require further consideration. 
 Pubmed 

The development of non-P-glycoprotein-mediated multi-drug resistance is a frequent event among lung-cancer cell lines. 
 Pubmed 

Background: Efflux pumps of the Resistance-Nodulation-cell Division superfamily confer multi-drug resistance to Gram-negative bacteria. 
 Pubmed 

In summary, there may be a significant contribution of transcriptional activation to multi-drug resistance. 
 Pubmed 

High Glo1 expression is a cause of multi-drug resistance. 
 Pubmed 

Usage of mdr in English

The mammalian mdr gene family comprises a small number of closely related genes. 
 Pubmed 

Expression levels of each mdr gene are dramatically different in various mouse tissues. 
 Pubmed 

Each of the mdr genes has a specific RNA transcript pattern. 
 Pubmed 

Tet could downregulate the level of mdr-1 gene and decrease the expression of P-gp. 
 Pubmed 

In addition, a number of strategies aimed at reversing the mdr phenotype are under study. 
 Pubmed 

H17 proved to be more active than cyclosporine A as a known strong mdr modulator. 
 Pubmed 

We have identified distinct mdr gene transcripts encoded by three separate mdr genes in the mouse. 
 Pubmed 

In this report, we characterize a second member of the mdr gene family which we designated mdr2. 
 Pubmed 

These results should be considered in relation to understanding the normal physiological function of the mdr multigene family. 
 Pubmed 

The mdr-1 level was measured in 44 biopsies from 19 patients. 
 Pubmed 

Our results demonstrate that overexpression of a single member of the mdr group is sufficient to confer drug resistance. 
 Pubmed 

It was previously demonstrated that multidrug-resistant Chinese hamster cell lines contain an amplified, transcriptionally active DNA sequence designated mdr. 
 Pubmed 

However, the direct relationship, if any, of this new member of the mdr family to multidrug resistance remains to be established. 
 Pubmed 

Multidrug resistance in mammalian tumor cells is associated with the overexpression of mdr genes encoding P-glycoproteins, which function as drug efflux pumps. 
 Pubmed 

Alternatively, some groups are investigating transfecting the mdr gene into bone marrow cells to reduce the sensitivity of these cells to cytotoxic agents. 
 Pubmed 

In these cell lines high levels of resistance are frequently associated with amplification and overexpression of a small group of genes termed mdr or gp170. 
 Pubmed 